At ICON's bioanalytical laboratories we understand the context of use principles for biomarker assays.
All biomarker assays are different and require careful consideration to ensure the assays are fit for their intended purpose. We offer different levels of biomarker assay characterisation based on your needs.
Acceptance criteria and the design of the validation studies are always discussed.
We have experience in running biomarker assays for various purposes on all our analytical platforms. This ranges from implementing a commercial ELISA kit, to a sensitive Ella assay, or a more complex kit implementation on the ultra-sensitive SMCxPro platform.
Biomarker assays on LC-MS/MS are also routinely developed. Our flow cytometry experts run mostly cell surface biomarkers.