All case studies

Highlights

We focus our innovation on the factors that matter most — accelerating time to market, reducing costs and enhancing quality. Learn more about our expertise in this selected number of case studies.

Delivering high quality at low cost

We created a more sustainable organisational design for our partner, wiith in their Data Management and Biostatistics functions, resulting in a 56% cost saving.

FSP partnership - sustained efficiency and ongoing innovation

The implementation of an FSP model across our partner's project management function, led to 20% cost efficiences and a 30% reduction in client burden.

Out-performing ambitions with strategic capacity management

Explore how we built a dedicated global infrastructure of functional hubs, reducing the cost per FTE by over 20% and resulting in 20% productivity savings.

By taking a site and patient-centric approach, and leveraging advanced tools and real-time data insights, we maximise patient access, recruitment, and retention—ensuring that every trial is conducted with efficiency, agility, and a commitment to improving patient outcomes.

All case studies

See all our case studies. You can filter by categories, selecting amongst our broad range of solutions.

Regulatory Strategy in Clinical Development (EU)

"A large pharma customer sought expert regulatory support from ICON for a paediatric rare disease development
program."

Increased compliance for complex Alzheimer’s disease study

The sponsor in this case was a large pharmaceutical company that contracted ICON to manage and streamline the training and compliance workload for their phase 2 Alzheimer’s study.

Multinational phase 1 biosimilar study

ICON conducted a multinational biosimilar phase 1 study for multiple sclerosis (MS). This trial was performed under high regulatory scrutiny and challenging pandemic conditions, with increased dosing targets requiring additional site activation.

Exceeding recruitment timelines in a double-blind multiple system atrophy (MSA) study

ICON conducted a multi-centre study to assess the efficacy, safety, and tolerability of an anti-α-synuclein human immunoglobulin G1 monoclonal antibody in patients with Multiple System Atrophy followed by an open label extension.

IVDR Technical File Remediation

ICON was tasked with developing a remediation program encompassing a product portfolio spanning more than seven automated instruments and more than 500 analytes or assays.

Voice & speech recognition

ICON Outcome Measures found well-validated tools for processing data associated with speech cadence, vocal pitch, and similar measures to evaluate rates of change in neurologic and psychiatric disorders.

Evolving quality oversight to limit sponsor burden

ICON implemented a Data Management Asset Lead (DMAL) role to provide oversight and ensure adherence to standards for a sponsor with limited bandwidth.

Patient cardiac safety

A digital health lead at a large pharmaceutical company came to ICON Outcome Measures to find a wearable that could capture continuous cardiac rhythms and be used to detect QT prolongation.

Applying statistical and programming expertise to overcome FDA challenges

ICON supported a biotech company in preparing for FDA submission by quickly mobilising a team to address unexpected comments on statistical analysis and data collection, resulting in timely BLA submission, enhanced data quality, and alignment with FDA requirements.

The importance of CRF design in cell and gene therapy studies

ICON partnered with a biotech sponsor to optimise Case Report Forms (CRFs) for an oncology cell and gene therapy trial. By adopting iRECIST criteria and standardising CRF templates, we reduced data duplication, ensured accuracy, and provided flexibility for subject re-treatment.

Global remote monitoring CRA hub

A complex oncology study in multiple myeloma cancer experienced a 30% higher than anticipated enrollment rate, leading to a large data backlog. Learn how ICON implemented global remote monitoring to address the backlog and manage ongoing data volume.

Language Services: Voiceover and video localisation

ICON provided a fully localised and tested informational solution for patients that was consistent across platform components for online materials developed to train patients on the consent process.

Solutions case studies

Our solutions span the entire lifecycle of product development and can be adapted to suit small local trials or large global programs. Explore our work in the different aspects of our solutions.

Let's collaborate

Discover how ICON's expertise transforms clinical trials.

Blogs

Stay informed with ICON's expert insights on clinical trials, regulatory changes, and industry trends. Our blogs provide practical advice, innovative solutions, and thought leadership from global experts.

News

Stay updated with our latest news on partnerships, financial results, technological advancements, and industry insights.

Insights

Explore ICON's expert analysis and practical advice on the latest operational, regulatory, and economic challenges in clinical research. Our insights provide thought leadership and innovative solutions to transform clinical trials.

Case studies

Highlights

Delivering high quality at low cost

FSP partnership - sustained efficiency and ongoing innovation

Out-performing ambitions with strategic capacity management

All case studies

Regulatory Strategy in Clinical Development (EU)

Increased compliance for complex Alzheimer’s disease study

Multinational phase 1 biosimilar study

Exceeding recruitment timelines in a double-blind multiple system atrophy (MSA) study

IVDR Technical File Remediation

Voice & speech recognition

Evolving quality oversight to limit sponsor burden

Patient cardiac safety

Applying statistical and programming expertise to overcome FDA challenges

The importance of CRF design in cell and gene therapy studies

Global remote monitoring CRA hub

Language Services: Voiceover and video localisation

Solutions case studies

Let's collaborate

Blogs

News

Insights