A mid-size pharmaceutical company conducted a phase II study to compare treatments in 52 adult patients with plaque psoriasis. The treatment was to be applied twice daily for 3 weeks in 10 US sites. The morning application was done at the site and the evening application was to be completed by the patient themselves. Busy patient lifestyles interfered with consistent site visits and ensuring that the evening application occurred as scheduled.

Accellacare In-Home Services (formerly Symphony Clinical Research) provided in-home visits for 2 of the 10 investigator sites. Initially, patients were asked to go to the site for the morning application and in-home clinicians were used for the evening application in patients’ homes or other convenient locations. Midway through the study, the 2 sites that utilised In-Home Services extended their use for both the morning and evening applications.

At the end of the study, the 2 sites that offered In-Home Services enrolled 50% of the required subjects for the entire study, enrolling on average, 3x more patients than the sites that did not use In-Home Services. The investigator sites that used In-Home Services had 100% confidence in compliance and the timing of the twice- daily applications. There were no missed visits or study dropouts. The study ended early with positive results from robust enrolment by sites using In-Home Services.

The addition of Accellacare In-Home Services not only helped to enrol the required patients ahead of schedule, but also helped to ensure compliance, improve convenience and flexibility for patients, and ease the site burden.