Wearables and remote patient monitoring in clinical trials

Accelerating and improving digital health technology selection

Navigating the shift from traditional trial models to agile, patient-centric processes driven by digital health technologies.

Personalising digital health

Incorporating digital health technologies into clinical trial designs has the potential to address many clinical trial challenges, including patient retention and engagement.

Addressing cybersecurity for your medical device

Cybersecurity vulnerabilities can emerge in any medical device that can be connected to another electronic device or network.

It's time to accelerate remote patient monitoring adoption

Remote patient monitoring makes it easier for patients to participate and improves recruitment through greater access to diverse patient populations.

The use and management of data from connected devices (wearables, sensors, smartphones, laptops, tablets), mobile platforms, and telemedicine, offers effective clinical care while protecting the patient with ongoing monitoring, ensuring participants and care providers remain connected wherever they are located.

Wearable devices and sensors also enable the collection of richer data and insights to enhance understanding of the effects of treatment and objective measures of intervention effects both in-clinic and in remote free-living settings.

Connecting and engaging patients

ICON Digital Platform gives patients more control and better access to personalised healthcare, right from their own devices and on their own schedule. Easy-to-use devices, with minimal set-up, makes engaging patients easier by integrating care into patients’ daily lives. Patients get full access to a powerful platform that offers interactive health sessions, educational content, and video conferencing.

However remote patient monitoring requires a robust strategy in data management, including digital endpoint validation and interpretation.

Our ICON Insights will help you to understand and successfully address the complexities of implementation of wearable devices in trial design, execution and reporting.

Factsheet: Wearables and digital endpoint validation

An end-to-end approach to managing wearable devices.

Whitepaper: Wearables and digital endpoint strategy and validation

Although mHealth devices and sensors are continuing to evolve, and it is now possible to capture a vast array of physiological data, the operationalization of digital trial is not without challenges.

Develop a strategy to identify devices that are "fit for purpose"
The ICON framework for Digital Endpoint selection and validation to ensure the outcome measurement is robust, reliable, and interpretable
Address the key considerations that arise when using digital technology to support endpoint generation in clinical studies such as Device Selection, Endpoint Reliability and Sensitivity, Meaningful Change Thresholds, and Analysis Strategy and Interpretation
Use our checklists for device selection and data strategy

Read the whitepaper

Wearables webinar recordings

Digital endpoint strategy and validation

The COVID-19 pandemic has heightened interest in mHealth and mobile technology to capture patient insights outside of the traditional clinical setting.

Best practices for implementing a successful digital trial

ICON and Intel explore industry concerns about implementation of this technology in a clinical trial, including patient acceptance, device suitability, data complexity and insight generation, operationalisation, privacy and security issues, and regulatory acceptance.

eCOA - insights into equivalence testing methodology and implications for BYOD

In this webinar, we review the accumulating evidence to support measurement equivalence of instruments when migrated to ePRO.

Smartphone sensors to measure novel health outcomes

This webinar explores the novel uses of smartphone sensor measurement in the areas of health, wellness and clinical research and appraises the promise of these approaches in clinical trials.

Activity monitoring setting standards for clinical research

With the introduction of sensors, wearables and apps we can fullly engage patients in real time to increase the quality of data.

Using wearables data to support drug reimbursement

In this webinar learn more about payer requirements for additional evidence, wearables as a potential solution, payer preparations for digital technologies, and more.

Media contributions on wearables, sensors and remote monitoring

Obesity trial surge puts the focus back on decentralisation

Explore the evolving obesity clinical trials landscape and the role of decentralisation and new technologies in this recent CTA article.

Interview with Andy Coravos

In this article, Andy Coravos, founder of HumanFirst, recently acquired by ICON, shares insights on leveraging digital health technologies and wearables to manage chronic conditions.

Current state of drug development, clinical trials and precision measures

This article provides an overview of a recent npj Nature publication, that proposes enough alignment exists between independent traditional COA and DHT libraries to build a single framework for researchers to identify and compare actively-collected versus passively-monitored tools for the same or similar measure.

Data integration frameworks key for embracing big data’s potential

Rick Rosenthal and Paula Fullman explain how to navigate the complexities and challenges of the evolving digital landscape of healthcare data.

ICON acquires HumanFirst to boost support for digital tools in clinical trials

This article from STAT covers ICON’s acquisition of HumanFirst, a cloud-based technology company supporting precision measurement in clinical trials.

IMI Mobilise-D: The next generation of mobility research

In this article, Gerard Quinn, VP, IT Innovation and Informatics, provides an overview on the Innovative Medicines Initiative (IMI) funded Mobilise-D project.

Beyond the glass: A look at digital pathology’s practical applications and novel possibilities in clinical trials

In this article from Diagnostics World News, Jenny Ross, Pathologist and Medical Director, looks at practical uses of digital pathology technologies and illustrates considerations for their use in global clinical trials.

Patient-first technology development increasing patient centricity

Carrye Nibblelink, Exec Director, Decentralised Clinical Trial Solutions explores how the ICON Digital Platform engages patients throughout their clinical trial journey.

The value of measuring sleep and activity in Alzheimer's disease trials.

Sleep quality and quantity have clinical relevance in Alzheimer's disease. Review the use of wearables in Alzheimer’s disease to provide objective measures of sleep and activity patterns that are not subject to patient recall bias.

Case studies on wearables, sensors and remote monitoring

Wearables and remote monitoring case study

ICON’s wearables and patient outcomes teams were able to objectively measure cough using patient-centric, novel technologies.

Remote patient monitoring for respiratory measures

Generating respiratory disease specific biomarkers using advanced analytics.

Developing and validating endpoints derived from wearables data

ICON uses AI machine learning algorithms to develop new digital biomarkers from raw accelerometer data.

Management wearables and data in a global trials

ICON’s eCOA team and wearables consultants design, implement and manage a technology solution for a global trial across nine countries amongst patients suffering from a neurological disorder.

Leveraging BYOD, wearables and shareables in Real World Evidence studies

Approaches to leveraging mobile, wearable and shareable technology in observational research

mHealth and wearables blogs

Blog: Part three: applications for wearables and apps in precision medicine

Patients increasingly act like consumers, expecting to control decisions about their care and to receive individualised products and services

Real World Data insights

ICON's real world data (RWD) continues to drive healthcare and research discussions and decisions. Stay up to date with the latest information that regulators, payers and providers demand.

Receive more insights on mHealth & Wearables from ICON

Please visit ICON's Preference Centre and select 'mHealth/Wearables' under 'Topics of Interest' to receive new insights on oncology.

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Remote Patient Monitoring