Solutions tailored to your pipeline
Experience, expertise and technology to support the development of innovative treatments and therapies
A trusted partner
ICON is committed to achieving success on your clinical development programs, supporting your future transformational goals and precision medicine focus. This content was specifically curated to give you access to helpful information as you develop and deliver new treatments for the most challenging conditions.
Transforming clinical research through innovation
ICON’s technology solutions are focused on the factors most critical to your needs. With expertise in technology harmonisation and systems integration, our innovative tools and platforms can be adopted smoothly, to enhance collaboration, increase transparency and drive productivity gains.
End-to-end eClinical Solutions
ICON is deploying decentralised clinical trials globally, in multiple therapeutic areas and will support you in navigating the assessment, planning and execution for better outcomes.
Central Laboratories
ICON offers a full range of central laboratory services dedicated to the delivery of high quality, harmonised data to facilitate the efficient and accurate assessment of drug efficacy and safety.
In-Home services
Reducing patient burden is especially important in oncology studies. Making it convenient for the patient to continue assessments and stay engaged in the trial will support the patient and help you to keep your trial on track. Accellacare In-Home Services can be provided in all phases and a wide range of therapeutic areas.
Medical Imaging
ICON delivers comprehensive medical imaging services across a broad range of therapeutic areas. Supported by leading edge technology platforms to streamline image collection, management and analysis, we help clients improve decision making, increase efficiency and potentially reduce study costs.
Advances in imaging biomarkers
Estimating drug efficacy with tumour growth rate modelling
This whitepaper compares the use of imaging biomarker methodologies such as RECIST 1.1 with novel tumour growth rate (TGR) modelling. Using this methodology eliminates the need for a comparable control arm which can reduce research costs. TGR modelling also more efficiently captures heterogeneous tumour measurements and whole-body tumour burden.
End-to-end cardiac safety support
ICON can help to assure the safety of all your clinical trial participants with end-to-end cardiac safety solutions, including electrocardiography (ECG), event monitoring, blood pressure monitoring (BPM), long-term Holter monitoring, echocardiography (ECHO) and multi-gated acquisition scan (MUGA) studies.
Addressing obesity's impact across the disease spectrum
As global obesity rates rise, the pressure to develop effective and scalable treatments is mounting. Read our latest whitepaper, survey and case study for insights to help guide clinical trial design and drug development strategies to support your pipeline.
Cardiovascular disorders
Experience in the last five years
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114
Studies -
3,000+
Sites worldwide -
21,100+
Patients
ICON has substantial expertise successfully managing the complexities of global, multicentre clinical trials involving cardiology disorders. We have a proven record in project management from early phase development to New Drug Application (NDA) submission. ICON has participated in pivotal and/or supportive trials and/or provided NDA/key Marketing Authorisation Application (MAA) support services that led to the market approval of 11 important new drug therapies for cardiovascular and metabolic indications.
Oncology and haematologic malignancy
Experience in the last five years
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47
Oncology drugs approved -
390+
Early phase oncology trials -
516
Solid tumour trials -
275
Haematologic malignancy trials
ICON is among the world’s leading CROs for oncology and hematologic malignancy drug development, having participated in pivotal and/or supportive trials and/or provided NDA/key Marketing Authorisation Application (MAA) support services that led to the market approval of over 40 important new drug therapies for oncology and hematologic malignancy indications.
Cell and gene therapy
Experience in the last five years
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171
CGT studies -
3,000+
Sites worldwide -
10,800+
Patients
Each Cell and Gene Therapy (CGT) study requires a personalised approach. By collaborating with our experts, your study will benefit from a customised strategy delivered with flexibility and expertise. Our experience and organisational structure allow us to support the needs of both large pharmaceutical companies and biotech CGT developers.
Boost trial efficiency with real-world intelligence and tokenisation
Late-stage research for immuno-oncology trials introduces unique challenges. ICON’s specialised services can address these through access to large-scale, patient-reported and real-world data, which can be visualised, aggregated, and analysed. In addition, we employ cutting-edge techniques to link clinical trial data to real-world and third-party data without compromising patients’ identity. The compounding power of tokenisation translates to the accumulation of intelligence, so clinical trials can achieve timely regulatory approval and utilise patient data beyond initial investment for pre-approval and commercialisation.
Webinar: Beyond the Token: Why Your Healthcare Data and Integration Strategy Matters
Whitepaper: The triad of trust: Navigating real-world healthcare data integration
Maximise immuno-oncology trial success through strategic decentralisation
With the rising cost and time to bring new drugs to market, and the need to increase patient diversity and retention, there is increasing demand for decentralised and hybrid immuno-oncology trials. ICON’s commercial connected health platforms, real-world data and information solutions—together with a global site network, home health services and wearables expertise—enable patient-centric decentralised and hybrid trial solutions.
Integrated endpoint management and adjudication solutions
Study endpoints are increasingly complex, and endpoint adjudication is becoming a focal point of regulators. With a key opinion leader network of 650 experts, ICON supports consistent reporting across regions and provides a quality control check through the clinical expert review of principal investigator reporting.
Our adaptable, client-oriented team has developed efficient processes to deliver successful results. Our integrated endpoint management capabilities (eCOA, ePRO), include rating-scale licensing through Mapi Research Trust, the holder of over 5,000 COAs and distributor of more than 600 questionnaires.
Following the acquisition of HumanFirst, ICON's ability to accelerate and improve digital health technology (DHT) selection to optimise protocol design is further enhanced.
Interactive Response Technology (IRT)
ICON’s IRT services are under-pinned by a team of experienced operational and technical professionals specially qualified in the design, development, and management of IRT solutions for randomisation and trial supply management throughout the life of the study.
Streamline site selection and study start up
The length and complexity of cardiovascular clinical trials make it hard to accurately estimate enrolment and study timelines. ICON can help you to navigate these challenges with an extensive global site network and industry-leading tools to support all aspects of feasibility and site identification.
One Search is ICON's proprietary, intuitive, integrated workflow and AI interrogation tool with access to multiple data sources. It provides the visualisation and data necessary for optimum site identification, to predict which sites have the highest probability to enrol subjects, based on ICON and broader industry data of capability, experience and performance.
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Contact
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In the News
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ICON’s advances on the perpetual path of innovation in laboratory solutions
Innovative laboratory solutions have the potential to optimise clinical research processes, create more efficient operations and improve sustainability to support wider organisational objectives. Learn about new initiatives to ensure the continued delivery of high-quality results that meet sponsors’ needs – today and tomorrow.
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Therapeutic Focus - Pushing Boundaries in Idiopathic Pulmonary Fibrosis Clinical Research
ICON's Laura Iliescu and Dr. Justin Herman explore the evolving landscape of idiopathic pulmonary fibrosis (IPF) drug development. With over 170 active clinical programs, IPF research is entering a transformative phase, driven by advances in composite endpoints, emerging biomarkers, and innovative clinical trial designs.
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Blending Models for Better Sourcing Solutions
There is a growing trend among large and midsize pharma in turning toward more strategic partnerships to help them navigate the increasing complexity of the development landscape and the compounding macroeconomic constraints.
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Obesity trial surge puts the focus back on decentralisation
Discover how decentralization and advances like wearables, telemedicine, and remote monitoring are enabling richer data collection and enhancing patient engagement in obesity clinical trials. Get insights on how innovations are reshaping trial designs, improving quality of life insights, and addressing the growing demand for efficient, long-term follow-up studies.
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Strategies for commercialising oncology treatments for young adults
This article explores the imperatives and strategies for commercialising oncology treatments targeting young adults, highlighting the need for innovative regulatory and commercial strategies to ensure successful market entry and improved patient outcomes.
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How AI can manage the risks and costs of postmarketing requirements
Postmarketing requirements (PMRs) for drug development are commonly required to gather data on a product’s longer-term safety, efficacy and optimal use. Carefully applied AI and machine learning offers the potential for better management of PMRs.
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Striking the right balance between transparency and privacy in clinical trial data sharing
In this article, our experts explore how to strike the right balance between adequately anonymising clinical trial data to protect participant privacy and company assets, while still preserving its value for research purposes.